Updated 12/23/2013
櫻井全 (さくらい あきら)
Neuroscience Institute
Georgia State University
P.O. Box 5030
Atlanta, GA 30302-5030
Tel: 404-413-5364
Fax: 404-413-5301
E-mail: akira(at)gsu.edu 


学歴:
Ph.D., 1998 筑波大学生物科学研究科
Thesis title: "Electrophysiological studies in acceleratory nervous regulation in the isopod crustacean Ligia exotica." 指導教官:山岸宏
B.Sc., 1993 筑波大学生物学類


職歴:
Jul 2008-現在 Research Scientist II, Neuroscience Institute, Georgia State University, Atlanta, Georgia.
Jun 2004-Jun 2008 Research Scientist I, Department of Biology, Georgia State University, Atlanta, Georgia.
Jul 2001-May 2004 Research Associate, Department of Biology, Georgia State University, Atlanta, Georgia.
Jul 2000-May 2001 東京医科歯科大学医歯学総合研究科・助手
Apr 2000-Jul 2000 東京都立大学・日本学術振興会特別研究員
May 1998-Mar 2000 Postdoctoral Fellow, Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada


発表論文:
  1. Gunaratne CA, Sakurai A, Katz PS (2013) Comparative mapping of GABA-immunoreactive neurons in the central nervous systems of nudibranch molluscs. J Comp Neurol, in press.
  2. Newcomb JM, Sakurai A, Lillvis JL, Gunaratne CA, and Katz PS (2012) Homology and homoplasy of swimming behaviors and neural circuits in the Nudipleura (Mollusca, Gastropoda, Opisthobranchia). In the Light of Evolution: Volume VI: Brain and Behavior, pp153-174.
  3. Newcomb JM, Sakurai A, Lillvis JL, Gunaratne CA, and Katz PS (2012) Homology and homoplasy of swimming behaviors and neural circuits in the Nudipleura (Mollusca, Gastropoda, Opisthobranchia). PNAS 109 Supplement 1: 10669-10676.
  4. Sakurai A, Newcomb JM, Lillvis JL and Katz PS (2011) Different roles for homologous interneurons in species exhibiting similar thythmic behaviors. Curr Biol 21: 1036-1043.
  5. Sakurai A and Katz PS (2009) Functional recovery after lesion of a central pattern generator. J Neurosci 29: 13115-13125. This paper was reviewed by Faculty of 1000 Biology (F1000 Factor 9.0). "Functional recovery of a structure such as the spinal cord after a lesion of the nervous system may depend on the re-establishment of axonal connections through regeneration/sprouting of descending pathways or else on plastic mechanisms within the spinal cord itself. Unfortunately, the cellular bases for the latter are lacking. This remarkable paper by Sakurai and Katz is a clear example of how simpler animal preparations (Tritonia diomedea) may shed light on mechanisms of the functional recovery of the swim escape behaviour that depends on plastic changes within such intrinsic circuitry after a central lesion." by Serge Rossignol (8 Jan 2010)
  6. Sakurai A and Katz PS (2009) State-, timing-, and pattern-dependent neuromodulation of synaptic strength by a serotonergic interneuron. J Neusosci 29: 268-279.
  7. Hill ES, Sakurai A, and Katz PS. (2008) Transient enhancement of spike-evoked calcium signaling by a serotonergic interneuron. J Neurophysiol 100: 2919-2928.
  8. Clemens S, Calin-Jageman RJ, Sakurai A, and Katz PS (2007) Altering cAMP levels within a central pattern generator modifies or disrupts rhythmic motor output. J Comp Physiol A 193: 1265-1271.
  9. Sakurai A, Calin-Jageman R, and Katz PS (2007) Potentiation phase of spike timing dependent neuromodulation by a serotonergic interneuron involves an increase in the fraction of transmitter release. J Neurophysiol 98: 1975-1987. This paper was reviewed by Faculty of 1000 Biology (F1000 Factor 3.0). "This careful study provides evidence that the 5HT-induced potentiation phase of spike-timing-dependent neuromodulation of the synaptic output of ventral swim interneuron B in the mollusk Tritonia diomedea is caused by an increase in the fraction of transmitter release." by John Hildebrand (27 Nov 2007)
  10. Sakurai A (2007) Spike timing-dependent neuromodulation in the Tritonia swim central pattern generator. Jpn Soc Comp Physiol Biochem 24: 18-26.
  11. Sakurai A, Darghouth NR., Butera RJ., and Katz PS (2006) Serotonergic enhancement of a 4-AP-sensitive current mediates the synaptic depression phase of spike timing-dependent neuromodulation. J Neurosci 26: 2010-2021.
  12. Yamagishi H, Miyamoto H, and Sakurai A (2004) Developmental changes in dopamine modulation of the heart in the isopod crustacean Ligia exotica: Reversal of chronotropic effect. Zool Sci 21: 917-922.
  13. Katz PS, Sakurai A, Clemens S, and Davis D (2004) The cycle period of a network oscillator is independent of membrane potential and spiking activity in individual central pattern generator neurons. J Neurophysiol 92: 1904-1917.
  14. Sakurai A and Katz PS (2003) Spike timing-dependent serotonergic neuromodulation of synaptic strength intrinsic to a central pattern generator circuit. J Neurosci 23: 10745-10755. This paper was reviewed by Faculty of 1000 Biology (F1000 Factor 6.0). "This paper shows that neuromodulation can be used to shape each oscillatory cycle of a pattern-generating circuit." by William Kristan (15 Dec 2003) 
  15. Sakurai A and Wilkens JL (2003) Tension sensitivity of the heart pacemaker neurons in the isopod crustacean Ligia pallasii. J Exp Biol 206: 105-115.
  16. Sakurai A (2001) Neuromuscular transmission in the heart of crustacean Ligia exotica. Jpn Soc Comp Physiol Biochem 18: 36-42.
  17. Sakurai A and Yamagishi H (2000) Graded neuromuscular transmission in the heart of the isopod crustacean Ligia exotica. J Exp Biol 203: 1447-1457.
  18. Sakurai A, Mori A, and Yamagishi H (1999) Acceleratory nervous regulation of juvenile myogenic hearts in the isopod crustacean Ligia exotica. Comp Biochem Physiol 124A: 575-580.
  19. Sakurai A, Mori A, and Yamagishi H (1999) Cardioinhibitory neurons in the isopod crustacean Ligia exotica. Zool Sci 16: 401-406.
  20. Sakurai A (1998) Electrophysiological studies in acceleratory nervous regulation of the heart in the isopod crustacean, Ligia exotica. Doctoral Thesis, University of Tsukuba.
  21. Yamagishi H, Sakurai A, and Mori A (1998) Isolation of neurogenic and myogenic activities by Joro spider toxin in the adult heart of the isopod crustacean Ligia exotica. Zool Sci 15: 673-676.
  22. Sakurai A, Mori A, and Yamagishi H (1998) Glutamatergic neuromuscular transmission in the heart of the isopod crustacean Ligia exotica. J Exp Biol 201: 2833-2842.
  23. Sakurai A and Yamagishi H (1998) Cardioacceleratory neurons in the isopod crustacean, Ligia exotica: Visualization of peripheral projection onto the heart muscle. Zool Sci 15: 19-25.
  24. Sakurai A and Yamagishi H (1998) Identification of cardioacceleratory neurons in the isopod crustacean, Ligia exotica and their effects on cardiac ganglion cells. J Comp Physiol A 182: 145-152.


賞与:
2000 吉田奨励賞(日本比較生理生化学会)
2004 Best Poster Award, South East Nerve Net Meeting
2005 Postdoctoral Travel Award, Society for Neuroscience Chapters


所属学会:
Society for Neuroscience
International Society for Neuroethology
日本比較生理生化学会


招待講演:
Jul 2000 吉田記念講演(日本比較生理生化学会)
Oct 2006 BMED 8813A / ECE 8803A: Hybrid Neural Microsystem, Georgia Institute of Technology.
Nov 2009 Biology4970 Undergraduate Seminar, Georgia State University.
Feb 2010 Neurobiology Seminar, University of Puerto Rico.
Jul 2010 Biology8700 Graduate Seminar, Georgia State University.
Jul 2012 Computational Neuroscience Workshop "Dynamics of rhythm generation."
Jul 2012 Computational Neuroscience Workshop "Principles of motor pattern generation: experiments and modeling."
Aug 2012 Symposium speaker, Tenth International Congress of Neuroethology.
Mar 2013 Platform Presenter, South East Neuroscience Consortium Meeting.
Nov 2013 Departmental Seminar, College of Charleston.


論文審査
Journal of Neuroscience
Journal of Neurophysiology
Frontiers in Invertebrate Physiology
日本比較生理生化学


役員等
1996-1998 日本比較生理生化学会・若手の会会長
2002-2004 日本比較生理生化学会・評議員
2004 South East Nerve Net, Steering committee
2006 South East Nerve Net, Steering committee 2008 South East Nerve Net, Steering committee
2010-2011 日本比較生理生化学会・評議員
2011- Review Editor, Frontiers in Invertebrate Physiology