BIOLOGY 6575
VIROLOGY
FALL SEMESTER 1999

Instructor: Dr. Teryl Frey                             Lecture: 4:30-7:00 PM Tuesday
Office: 418 Science Annex                           Room: 300 Classroom South
Office Phone: 651-3105
Email: tfrey@gsu.edu
Home Page: www.gsu.edu/~biotkf
Office Hours: 3:00-4:00 Tuesday

Text: Medical Virology, Fourth Edition, by D.O. White and F.J. Fenner, Academic Press

Lecture Notes: Lecture notes will be available on the instructor's home page for a
                        period of one week prior through one week after the specific lecture

Grading: 500 possible points

Exam I         Sept. 28         100 points

Exam II        Nov. 2             100 points

Exam III     Tues., Dec. 14     100 points

Term Paper I                         100 points

Term Paper II                         100 points

Grade Scale: A = 90-100; B= 80-89; C = 70-79; D = 60-69; F <60

Examinations: will be one hour in length and will consist of 50% short answer, definition and true-false questions and 50% essay questions. To assist students in preparation for the exams, one week before each exam a set of study questions from the lecture material will be available on the instructor's home page. Some of these questions will appear on the exam. Each exam will cover material presented since the previous exam; none of the exams will be cumulative in nature.

Make-up exam policy: One make-up exam will be allowed if a valid excuse is presented before the scheduled exam time. The make-up exam will be given on Tuesday, Dec. 7, and will consist of material covered on both Exams I and II.

Term Papers: Students will prepare two term papers.

Term Paper I will be a review of a book on virology available in the popular press (either fiction or nonfiction). After obtaining the book, students will bring their copy to class on either Aug. 31 or Sept. 7 to obtain instructor approval. After reading the book, students will prepare a five page (double spaced, 12 point, 1" margins) review of the book. The review should include: the author's background and motivation for writing the book, a summary of the book's contents, a general critique of the book including interest angles and insights which the book offers. The review will be concluded by a recommendation (zero to five stars) and a paragraph summarizing the recommendation. Term Paper I is due on Tuesday, Oct. 5.

Term Paper II will be a review of two or more original research articles on a topic of virology of interest to the student. Students will research the recent original research literature to find two papers related to the same research topic (either from the same or different labs). These papers will be submitted to the instructor on Tuesday, Oct. 12 and will be returned with suggestions by Tuesday, Oct. 19. The paper will be a minimum of ten pages of text (double-spaced, 12 point, 1" margins). The paper will contain an introduction to the topic (supported by background literature independent of the research articles), a description of the experimental approach taken in each article and the findings made, and a summary discussion of the progress made and future directions needed to be taken. If appropriate, a critique of the experimentation may be done. Literature used in preparation of the paper will be included in a Bibliography with appropriate citation in the text. Term Paper II is due on Tuesday, Nov. 30.

Attendance policy: Attendance of the instructor's lectures is not required. However, attendance of the guest lecturer's presentations is required. Each guest lecture absence will result in a 15 point deduction from the final grade.
 
 

TENTATIVE SCHEDULE (REVISED 11/16/99)

DATE                 TOPIC                                                 TEXT ASSIGNMENT

Aug. 24  Introduction to Virology

Virion Structure                                        Chapter 1

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Aug. 31 Viral Taxonomy                                         Chapter 2

Viral Replication Cycles                              Chapters 3 & 5

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Sept. 7 Viral Genetics                                             Chapter 4

BOOK REVIEW SELECTIONS FOR TERM PAPER I DUE

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Sept. 14 RNA Viruses                                             Chapter 3

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Sept. 21 DNA Viruses                                             Chapter 3

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Sept. 28         EXAM I

                        Human Papilloma Viruses; Guest Lecture by Dr. Joseph Icenogle, CDC

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Oct. 5 Retroviruses and HIV                                 Chapters 3 & 35

                    TERM PAPER I DUE

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Oct. 12 Viral Pathogenesis I                                     Chapter 5-7

            RESEARCH ARTICLES FOR TERM PAPER II DUE

Oct. 16     LAST DAY TO WITHDRAW AND RECEIVE A "W"

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Oct. 19 Viral Immunology                                         Chapter 8

Viral Pathogenesis II                                     Chapters 9-10
    More on Viral Pathogenesis
 

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Oct. 26 Viral Oncogenesis                                         Chapter 11

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Nov. 2        EXAM II

                    Herpes B Virus; Guest Lecture by Dr. Julia Hilliard, GSU

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Nov. 9 Viral Epidemiology                                         Chapter 14

                New and Emerging Viruses

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Nov. 16 Immunization Against Virus Disease             Chapter 13

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Nov. 23     Dangerous Virus Pathogens; Guest Lecture by Dr. Richard Meyer, CDC

Nov. 25         THANKSGIVING HOLIDAY

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Nov. 30 Viral Diagnosis                                             Chapter 12

Antiviral Chemotherapy                                 Chapter 16

                TERM PAPER II DUE

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Dec. 14     EXAM III @ 7:15 PM

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