BIOL3800/7800

PRACTICE PROBLEMS FOR EXAM 4

ANSWERS WILL BE POSTED OUTSIDE OF 413 SCIENCE ANNEX

4. (4 pts.) Give one unique feature for each of the receptor types and give one feature common to all three receptor types. UNIQUE FEATURE: Intracellular receptors

G-protein linked receptors (don't put "linked to G-proteins"!)

Tyrosine kinase receptors (don't put "tyrosine kinase")

COMMON FEATURE OF ALL:

5. (4 pts.) Write increase, decrease, or stays the same to indicate how the levels of cAMP are affected by each of the following:

a. G-protein bound to a form of GTP which cannot be hydrolyzed to GDP____________________________

b. mutation of the receptor so it cannot bind the ligand ____________________________________________

c. large decrease in the levels of ATP __________________________________________________________

d. mutation in adenlyate cyclase that inactivates it ________________________________________________

9. (3 pts.) Below are listed three different kinases. Give the name of one molecule that activates them.

1. Protein Kinase C - Activator ____________________________________

2. Protein Kinase A - Activator ____________________________________

3. Tyrosine kinase receptor - Activator _____________________________________