Credit Hour(s): 3.0
Fundamentals of Chemical Analysis. Prerequisites: Chem 3410 and Math 2212 with grades of C or higher. Two lecture and four laboratory hours a week. Chemical equilibria of acid-base systems, metal ion complexes and solubility, and their relationship to chemical analysis, using manual and semiautomatic methods of data collection.
Credit Hour(s): 3.0
Instrumental Methods I: Chromatography. Prerequisite: Chem 6000 with grade of B or higher. Corequisite: Chem 6110. Two lecture and three laboratory hours a week. Modern methods, e.g., gas, liquid, thin layer, column, and ion exclusion chromatographic techniques, used to demonstrate the principles of chromatography.
Credit Hour(s): 3.0
Separation in Biosciences. Prerequisites: Chem 6000 and 6010 with grades of B or higher, or equivalent. Two lecture and three laboratory hours per week. Analytical chemistry applications of electrophoresis, gel chromatography precipitation, and ultracentrifugation to molecular recognition and separations in biological systems.
Credit Hour(s): 2.0
Introduction to Fourier-Transform NMR Spectroscopy. Prerequisites: demonstrated research need and approval of the departmental chair. Introduction to techniques of Fourier-Transform Nuclear Magnetic Resonance Spectroscopy
Credit Hour(s): 3.0
Chemical Literature. Prerequisites: Chem 3110 with grade of B or higher, or equivalent, and consent of instructor. Introduction to the chemical literature. Emphasis on literature searching via database services.
Credit Hour(s): 3.0
Physical Chemistry I. Prerequisites: Chem 3410, Math 2212, Phys 2211K, and Phys 2212K with grades of C or higher, or equivalents. Three lecture hours a week. Principles of thermodynamics, transport, and kinetics, and how they serve as a basis for interpreting and interrelating the properties of matter.
Credit Hour(s): 3.0
Physical Chemistry II. Prerequisites: Chem 3410, Math 2212, Phys 2211K, and Phys 2212K with grades of C or higher. Three lecture hours a week. Quantum mechanics and statistical mechanics, and how they serve as a basis for interpreting and interrelating the properties of matter.
Credit Hour(s): 3.0
Introduction to Biophysical Chemistry. Prerequisite: Math 2212 with grade of C or higher, or equivalent. Not acceptable for credit toward a degree in chemistry. Thermodynamics, theories of solution, and principles of dynamics applied to biological systems.
Credit Hour(s): 3.0
Instrumental Methods III: Spectroscopy. Prerequisites: Chem 6000 and 6120 with grades of B or higher, or equivalent. Two lectures and three laboratory hours a week. Modern spectroscopic techniques including an introduction to Fourier-Transform theory and their application to chemical problems. The results of quantum mechanics will be used as a guide in the analysis of spectra.
Credit Hour(s): 3.0
Inorganic Chemistry. Prerequisite: Chem 6120 with grade of B or higher. Periodic relationship of the elements and their compounds, including those less commonly encountered. Bonding, reaction mechanisms, complexes, and stereo-chemistry are among the topics discussed.
Credit Hour(s): 3.0
Biometallochemistry. Prerequisite: one year of organic chemistry (Chem 3410) and one semester of biochemistry (Chem 4600) with grade of B or higher. An exploration of the structural and functional use of metals in biological systems including metalloproteins and metallocomplex interaction with nucleic acids.
Credit Hour(s): 5.0
Metals in Biology and Medicine Prerequisite: Chem 6600 or equivalent, with B or higher. Overview of the roles of metals in biology and medicine, focusing on the metal-binding ability of proteins and nucleic acids and their relations to various disease states. Emphasis will be on the mechanism of metal-dependent enzymes. Topics include oxygen activation by metal ions, production of reactive oxygen species (ROS) in biological systems, metal uptake and toxicity, metal-assisted amino acid radical productions, metals in medicine, and biomineralization. An overview of bioinformatics and the key instrumental methods used in bioinorganic chemistry will be covered.
Credit Hour(s): 3.0
Advanced Synthesis. Prerequisite: one year organic chemistry with laboratory (Chem 3110) with grade of B or higher, or equivalent. Two lecture and four laboratory hours a week. Synthesis and characterization of inorganic and organic compounds by modern methodology.
Credit Hour(s): 3.0
Polymer Chemistry. Prerequisites: Chem 3410 and 6110 with grades of B or higher, or equivalent. Introduction to polymer synthesis, properties and characterization. Topics include: reaction mechanisms, molecular weight determination, thermodynamics and chain statistics, rubber elasticity, and transport properties of dilute polymer solutions.
Credit Hour(s): 3.0
Mechanistic Organic Chemistry. Prerequisite: one year of organic chemistry (Chem 3410) with grade of B or higher. Experimental approaches to determining the mechanisms of chemical reactions in organic chemistry.
Credit Hour(s): 3.0
Bioorganic Chemistry. Prerequisite: one year of organic chemistry (Chem 3410) or a course in biochemistry with grade of C or higher. Strategies for designing pharmaceutical agents to inhibit enzymes. This is a writing intensive course.
Credit Hour(s): 3.0
Drug Discovery: Theory and Practice. Prerequisites: Chem 2400 and Chem 3410 with grades of B or higher, or consent of instructor. Three lecture hours a week. Study of the principles of drug design, drug design methods, and tools commonly used in the pharmaceutical industry, and general strategies and common pitfalls in drug discovery.
Credit Hour(s): 3.0
Advanced Synthesis & Mechanism in Organic Chemistry. Prerequisite: consent of instructor. This course focuses on advanced synthetic methodologies and reactions mechanisms.
Credit Hour(s): 5.0
Practicum in Biotechnology. Prerequisite: consent of instructor and the Biotechnology Committee. Laboratory training and experience related to Biotechnology. Both technique and project-based rotations will be offered. May be repeated up to three times if projects or rotations change.
Credit Hour(s): 3.0
Molecular Modeling Methods. Prerequisites: Chem 3410 and 6110 with grades of B or higher, or equivalent, and consent of instructor. Molecular mechanics/dynamics methods to solve structural problems in organic, bioorganic, and biophysical chemistry. May be repeated if topics are different.
Credit Hour(s): 3.0
Special Topics in Organic Chemistry. Prerequisite: Chem 3410 with grade of B or higher, or equivalent. May be repeated if topics are different. Advanced topics in organic chemistry as may fit the needs and interests of the students and faculty. Such topics might be stereoisomerism, heterocycles, alkaloids, organic mechanisms, structure-activity relationships.
Credit Hour(s): 3.0
Special Topics in Physical Chemistry. Prerequisite: Chem 6120 with grade of B or higher, or equivalent. May be repeated if topics are different. Advanced topics in physical chemistry as may fit the needs and interests of the students and faculty. Such topics might be chemical kinetics, statistical mechanics, quantum mechanics, molecular spectra, phase equilibrium.
Credit Hour(s): 5.0
Biochemistry I. Prerequisite: Chem 3410 with grade of C or higher, or equivalent. Five lecture hours a week. Introduction to biochemical phenomena: proteins, enzymes, vitamins, carbohydrates, lipids, nucleic acids, DNA, RNA, and metabolism.
Credit Hour(s): 3.0
Biochemistry II. Prerequisite: Chem 3410 with grade or B or higher. Three lecture hours a week. Introduction to biochemical phenomena: proteins, enzymes, vitamins, carbohydrates, lipids, nucleic acids, DNA, RNA, and metabolism.
Credit Hour(s): 3.0
Enzymology. Prerequisite: one year of organic chemistry (Chem 3410) with grade of C or higher and one semester of biochemistry (Chem 6600) with grade of B or higher, or equivalents. (Same as Biol 6630.) Introduction to enzyme catalysis, with emphasis on the general concepts of enzyme kinetics and the common tools for studying enzymes.
Credit Hour(s): 4.0
Fundamentals of Bioinformatics. Prerequisites: Biol 3800 with grade of C or higher, or equivalent, or written approval of instructor. (Same as Biol 6640 and CSc 6640.) Four lecture hours per week. A "hands-on" approach to bioinformatics using PCs, the internet, and computer graphics to analyze, correlate, and extract information from biological databases, emphasizing sequence and structure databases for proteins and nucleic acids, and introducing the computing skills necessary for bioinformatics. Topics include: sequences and three- dimensional structures of proteins and nucleic acids, the major databases, algorithms for sequence comparison, data mining, and prediction of structure and function.
Credit Hour(s): 3.0
Nucleic Acid Synthesis and Drug Design. Prerequisite: consent of instructor. Lectures on nucleic acid synthesis, mechanism, therapeutics, and detection. Course may be repeated.
Credit Hour(s): 3.0
Biomolecular Simulations. Prerequisites: Chem 3410 and Chem 4120 or equivalents with grades of C or higher, or consent of instructor. (Same as Chem 6780.) This is an introductory self-contained course on the application of molecular dynamics and related methodologies by which student with a relatively limited background in chemistry, biology, and computer literacy can learn the fundamentals of research in these areas. In this course, students will learn to do computer calculations that quantify biomolecular interaction concepts discussed in lectures in biology, biochemistry, and biophysics.
Credit Hour(s): 3.0
Advanced Analytical Chemistry. Prerequisite: consent of instructor. Advanced theories and methods of analytical chemistry. May be repeated if topics are different.
Credit Hour(s): 2.0
Analytical Laboratory. Prerequisite: consent of instructor. One lecture and three laboratory hours a week. Fundamental principles of analytical chemistry as applied to modern analytical problems.
Credit Hour(s): 3.0
Bioanalytical Chemistry I. Prerequisite: Chem 6190 with grade of B or higher, or consent of instructor. Basic concepts of analytical chemistry as applied to biologically-oriented problems.
Credit Hour(s): 3.0
Bioanalytical Chemistry II. Prerequisite: Chem 6850 with grade of B or higher, or equivalent or consent of instructor. Basic principles underlying instrumentation, automation, and laboratory computers used in solving bioanalysis problems.
Credit Hour(s): 3.0
Electrochemical Methods. Prerequisite: Chem 4110 with grade of B or higher, or equivalent. Three lecture hours a week. Fundamentals of electrochemistry and application to chemical problems. Special emphasis on electrode reaction mechanisms and interpretation of electrochemical results for organic, inorganic, and biological systems.
Credit Hour(s): 2.0
Responsible Conduct of Research in Chemistry. Two lecture hours a week. Responsible conduct of research in chemistry with emphasis on ethics of conducting research, data analysis, conformance to federal and community guidelines, and safety in the chemistry laboratory.
Credit Hour(s): 2.0
Advanced Research Methods. Corequisite: concurrent enrollment in Chem 8910, Chem 8999, or Chem 9999. Two lecture hours a week. Student learning of interdisciplinary experimental strategies and laboratory procedures in chemistry.
Credit Hour(s): 2.0
Theme-Based Chemistry Laboratory. Prerequisite: Biol 3810 with grade of C or higher. Students will work in small groups to develop specific biological or chemical hypotheses, design and carry out experiments to test these hypotheses, and analyze the results they obtain. Topics will vary.
Credit Hour(s): 3.0
Essentials of General Chemistry. Three lecture hours a week. Essentials of mass relationships, solutions, gas laws, calorimetry, atomic structure, oxidation/reduction, and chemical nomenclature. For secondary school science teachers not teaching chemistry.
Credit Hour(s): 3.0
Foundations of General Chemistry I. Prerequisite: Chem 7000 with grade of B or higher, or equivalent. Three lecture hours a week. Principles of atomic structure, chemical bonding, and molecular structure. For secondary school teachers. Cannot be used for a graduate degree in chemistry.
Credit Hour(s): 3.0
Foundations of General Chemistry II. Prerequisite: Chem 7010 with grade of B or higher, or equivalent. Three lecture hours a week. Principles of chemical equilibrium, thermochemistry, acid/base theories, and electro-chemistry. For secondary school chemistry teachers. Cannot be used for a graduate degree in chemistry.
Credit Hour(s): 1.0 TO 5.0
Directed Study in Chemistry. Prerequisite: consent of instructor and advisor. Laboratory and recitations to be arranged. Directed study in areas of special interest to teachers or teacher candidates. May be repeated if topics vary.
Credit Hour(s): 1.0 TO 5.0
Directed Research in Chemical Education. Combined credit received for Chem 7900 and 7910 must not exceed fourteen hours. May be repeated if topics vary.
Credit Hour(s): 3.0
Protein Structure and Function. Prerequisite: Chem 6610 with grade of B or higher, or consent of instructor. (Same as Neur 8200.) Discussion of the structure and function of proteins and of enzyme mechanisms. Topics include protein folding and motions, descriptions of enzyme catalysis at a molecular level, consideration of the energetics of biological processes, and enzyme kinetics.
Credit Hour(s): 3.0
Nucleic Acid Structure and Function. Prerequisite: Chem 6610 with grade of B or higher, or consent of instructor. (Same as Biol 8637 and Neur 8210.) Topics include the structure of nucleic acids, mechanism and control of DNA and RNA synthesis, and interaction of proteins and drugs with nucleic acids.
Credit Hour(s): 3.0
Medicinal Chemistry. Prerequisite: consent of instructor. Study of the isolation, characterization, and elucidation of structure and synthesis of medicinally important compounds. The relationship between chemical structure and biological activity of selected drugs, vitamins, hormones, and proteins is reviewed.
Credit Hour(s): 3.0
NMR Spectroscopy for Organic Chemists. Prerequisite: Chem 6050 or the consent of the instructor. Theory and application of NMR spectroscopy for characterization and structure elucidation of organic molecules.
Credit Hour(s): 4.0
NMR Spectroscopy. Prerequisite: Chem 6050 or consent of the instructor. Theory and application of NMR spectroscopy for the characterization and elucidation of organic and biological molecules.
Credit Hour(s): 3.0
Interaction of Electromagnetic Radiation with Matter. Prerequisite: consent of instructor. Magnetic resonance, infrared, Raman, visible, and ultraviolet spectral phenomena.
Credit Hour(s): 4.0
Biophysical Chemistry. Prerequisite: Chem 6110 and 6120 or Chem 6190 with grade of B or higher, or equivalent, or consent of instructor. Applications of quantitative physical techniques to biomolecules, especially proteins and nucleic acids.
Credit Hour(s): 3.0
Computational Chemistry. Prerequisite: Chem 6110 and Chem 6120 with grades of B or higher, or equivalent. Two lecture and two laboratory hours a week. Application of current computational chemistry programs to research problems or projects.
Credit Hour(s): 3.0
Biomolecular Nuclear Magnetic Resonance. Prerequisite: introductory courses in spectroscopy, such as Chem 4050/6050 and Chem 4190/6190 with grade of B or higher, or equivalent. Some experience in the application of quantum mechanics in spectroscopy is useful, but not essential. Experimental design and interpretation of nuclear magnet resonance data, particulary with respect to applications in structural biology.
Credit Hour(s): 3.0
Advanced Topics in Biochemistry. Prerequisite: consent of instructor. Biochemical areas emphasized may include carbohydrates, lipids, nucleic acids, proteins, enzymes, immunochemistry, electron transport, and oxidative and photosynthetic phosphorylation. May be repeated if topics vary.
Credit Hour(s): 4.0
Advanced Bioinformatics. Prerequisites: Chem 6640 or equivalent, ability to program in Java or C++ or equivalent, and consent of instructor. (Same as Biol 8630 and CSc 8630.) Advanced topics in bioinformatics, computer and internet tools, and their applications. Computer skills for the analysis and extraction of functional information from biological databases for sequence and structure of nucleic acids and proteins. Students will complete a computer-based bioinformatics project.
Credit Hour(s): 1.0
Seminar in Chemistry. Prerequisite: departmental consent. Discussion of current research areas in chemistry.
Credit Hour(s): 3.0
Graduate Seminar in Chemistry. Prerequisite: Graduate standing in the Department of Chemistry at Georgia State University. This course deals with the process of giving a scientific seminar. Focus is on production of professional slides, the details of the oral presentation, and development of the ability to answer questions on the material. The course may be repeated.
Credit Hour(s): 1.0 TO 4.0
Non-Thesis Paper Writing. Prerequisite: consent of instructor and the Biotechnology Committee. Students will write a non-thesis paper based on a review of the literature.
Credit Hour(s): 1.0 TO 5.0
Directed Study in Chemistry. Prerequisite: departmental consent. May be repeated if topics vary.
Credit Hour(s): 1.0 TO 15.0
Directed Research in Chemistry. May be repeated if topics vary.
Credit Hour(s): 3.0
Practicum in Chemistry: Laboratory Supervision. Introduces graduate students to the techniques of good laboratory supervision. This course or its equivalent is required of all chemistry graduate students who serve as laboratory assistants. Credit does not count toward graduation.
Credit Hour(s): 1.0 TO 2.0
Topics in Molecular Biological Sciences. (Same as Biol 8970.) May be repeated if topics vary. May be taken for one or two credit hours.
Credit Hour(s): 1.0 TO 18.0
Thesis Research.
Credit Hour(s): 1.0 TO 18.0
Dissertation Research.