Iroduction| Invitation| Exploration| Explanation| TakingAction | Conclusion
Doctors and scientists around the world are trying to develop new drugs to treat AIDS. Read about 'How to Ease Suffering' and 'Give Hope' to those who are in pain. abcnewssegment on availability of aids See how these professionals rely upon molecular shape to design new drugs in the treatments of disease.
Your team is going to investigate Molecular Models. How these models are formed and how they impact medical research.
You will begin by:
1. You will find the materials to set up the molecular models for the wonder drug in your research kit. Use the materials and instructions located there to find how to assemble the basic molecular models needed in order to begin the research. Do this research first. In order to keep track of these molecular shapes make sure that you make at least one digital photograph of your investigation, and load it onto your work station computer. Seek help if you are not sure how to do this, as well as copy images from the Internet. Write a brief summary of your research and post it on the project bulletinboard.
2. After building the basics, see how other scientists are using molecular shapes to discover new drugs in the treatment of AIDS.
To understand why water has such special properties, however, we must examine it at the atomic level. Water is an example of a compound. The density is a constant ratio of mass to volume. Ice floats on water because ice has a lower density than water. Ice is less dense than water because it contains fewer water molecules in a given amount of space.
You will begin by:
1. Determining the density of water and ice.
2. Perform the water experiment from the handout provided.
3. Fill in your analysis results on the appropriate Tables. Make sure all of the graph axes are labeled.
4. Each group will share their results with the class as part of the discussion.
Carbon has four electrons in its valence shell(outershell). Since this energy shell can hold eight electrons, each carbon atom can share electrons with up to four different atoms. Carbon can combine with other elements as well as with itself. This allows carbon to form many different compounds of varying size and shape.
You will begin by:
1. Investigating the bonding ability of carbon by building a model of a fullerene, a recently discovered class of compounds.
2. You will find instructions for building the Icosahedron in your research kit. The size is up to you, but make it visiblewith a minimum size of no less than five inches.
After answering the questions below, make a chart showing your data for each exploration. You will share and exchange information with other groups in the class through oral presentations.
Model Making Questions:
1. What shape does the water molecule have?
2. What are the bond angles in a tetrahedral shape molecule?
3. Give an example of a tetrahedral shape molecule?
4. What shape has bond angles of 120o ?
5. Give an example of a molecule with the shape you described in #4.
6. What two basic patterns form your icosahedron model?
7. Why do you think carbon is a good choice for designing new drugs?
1. What chemical elements would medical nanorobots be made of?
2. How would chemical agents (e.g. AZT-drug) be transported and delivered to a target cell?
3. What would be the biggest benefit to be gained for human society from nanomedicine?
Hopefully you have gained some new insights into molecular shapes and have gotten an appreciation for the development of new drugs. For further research you may check other websites created by other researchers, such as Richard Feynman.
Contact: JackHassard for questions orcomments.